By combining our knowledge of the drug discovery process with our technical expertise, we can undertake complex research studies in order to help our client advance their drug discovery projects. Ensigna Biosystems can help you with the design, implementation and interpretation of the preclinical studies needed for the discovery of targeted therapies. Translational medicine strives to answer two important questions:
Who should get my drug?
Is my drug doing what it was designed to do?
Ensigna Biosystems offers the following services to address these questions:
Analysis of pharmacodynamic markers in efficacy studies, measurements by IHC, in situ hybridization, TaqMan® or Nanostring®
Pharmacogenomics and toxicogenomics: Generation of gene signatures in response to drug treatments
Tumor characterization and molecular sub-typing
Investigative pathology, histopathology consultation, laboratory animals phenotyping
Tissue cross-reactivity (TCR) studies